1f05

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Template:STRUCTURE 1f05

Contents

CRYSTAL STRUCTURE OF HUMAN TRANSALDOLASE

Template:ABSTRACT PUBMED 10869557

Disease

[TALDO_HUMAN] Defects in TALDO1 are the cause of transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]. It results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris.

Function

[TALDO_HUMAN] Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

About this Structure

1f05 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Thorell S, Gergely P Jr, Banki K, Perl A, Schneider G. The three-dimensional structure of human transaldolase. FEBS Lett. 2000 Jun 23;475(3):205-8. PMID:10869557

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