1ayr

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Template:STRUCTURE 1ayr

Contents

ARRESTIN FROM BOVINE ROD OUTER SEGMENTS

Template:ABSTRACT PUBMED 9495348

Disease

[ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.

Function

[ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.

About this Structure

1ayr is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Granzin J, Wilden U, Choe HW, Labahn J, Krafft B, Buldt G. X-ray crystal structure of arrestin from bovine rod outer segments. Nature. 1998 Feb 26;391(6670):918-21. PMID:9495348 doi:10.1038/36147

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