3kxu

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Template:STRUCTURE 3kxu

Contents 1 Crystal structure of human ferritin FTL498InsTC pathogenic mutant 2 Function 3 About this Structure 4 See Also 5 Reference

Crystal structure of human ferritin FTL498InsTC pathogenic mutant

Template:ABSTRACT PUBMED 20159981

Function

[Q6S4P3_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis (By similarity).[RuleBase:RU000622]

About this Structure

3kxu is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Ferritin

Reference

• Luscieti S, Santambrogio P, Langlois d'Estaintot B, Granier T, Cozzi A, Poli M, Gallois B, Finazzi D, Cattaneo A, Levi S, Arosio P. Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J Biol Chem. 2010 Apr 16;285(16):11948-57. Epub 2010 Feb 16. PMID:20159981 doi:10.1074/jbc.M109.096404