2epr

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 2epr

Contents 1 Solution structure of the secound zinc finger domain of Zinc finger protein 278 2 Disease 3 Function 4 About this Structure 5 See Also 6 Reference

Solution structure of the secound zinc finger domain of Zinc finger protein 278

Disease

[PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.

Function

[PATZ1_HUMAN] Transcriptional repressor.^[1]

About this Structure

2epr is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

• Zinc Fingers

Reference

1. ↑ Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L. A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem. 2000 Mar 17;275(11):7894-901. PMID:10713105