2xzb

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Template:STRUCTURE 2xzb

Contents 1 Pig Gastric H,K-ATPase with bound BeF and SCH28080 2 Disease 3 Function 4 About this Structure 5 See Also 6 Reference

Pig Gastric H,K-ATPase with bound BeF and SCH28080

Template:ABSTRACT PUBMED 21224846

Disease

[ATP4B_PIG] Note=Parietal cell autoantigen associated with autoimmune gastritis.

Function

[ATP4A_PIG] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.

About this Structure

2xzb is a 2 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

See Also

• ATPase

Reference

• Abe K, Tani K, Fujiyoshi Y. Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant. Nat Commun. 2011 Jan;2(1):155. PMID:21224846 doi:10.1038/ncomms1154