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2ftu

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Template:STRUCTURE 2ftu

Contents

solution structure of domain 3 of RAP

Template:ABSTRACT PUBMED 16678114

Disease

[AMRP_HUMAN] Note=In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.

Function

[AMRP_HUMAN] Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.

About this Structure

2ftu is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Lee D, Walsh JD, Mikhailenko I, Yu P, Migliorini M, Wu Y, Krueger S, Curtis JE, Harris B, Lockett S, Blacklow SC, Strickland DK, Wang YX. RAP uses a histidine switch to regulate its interaction with LRP in the ER and Golgi. Mol Cell. 2006 May 5;22(3):423-30. PMID:16678114 doi:10.1016/j.molcel.2006.04.011

Proteopedia Page Contributors and Editors (what is this?)

OCA

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