2w44

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Template:STRUCTURE 2w44

Contents

STRUCTURE DELTAA1-A4 INSULIN

Template:ABSTRACT PUBMED 020568733

Function

[A6XGL2_HUMAN] Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).[SAAS:SAAS022353_004_028339]

About this Structure

2w44 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Thorsoe KS, Schlein M, Steensgaard DB, Brandt J, Schluckebier G, Naver H. Kinetic evidence for the sequential association of insulin binding sites 1 and 2 to the insulin receptor and the influence of receptor isoform. Biochemistry. 2010 Jul 27;49(29):6234-46. PMID:20568733 doi:10.1021/bi1000118

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