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2eps

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Template:STRUCTURE 2eps

Contents

Solution structure of the 4th zinc finger domain of Zinc finger protein 278

Disease

[PATZ1_HUMAN] Note=A chromosomal aberration involving PATZ1 is associated with small round cell sarcoma. Translocation t(1;22)(p36.1;q12) with EWSR1.

Function

[PATZ1_HUMAN] Transcriptional repressor.[1]

About this Structure

2eps is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

See Also

Reference

  1. Fedele M, Benvenuto G, Pero R, Majello B, Battista S, Lembo F, Vollono E, Day PM, Santoro M, Lania L, Bruni CB, Fusco A, Chiariotti L. A novel member of the BTB/POZ family, PATZ, associates with the RNF4 RING finger protein and acts as a transcriptional repressor. J Biol Chem. 2000 Mar 17;275(11):7894-901. PMID:10713105

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