1a4j

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Template:STRUCTURE 1a4j

Contents

DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR

Template:ABSTRACT PUBMED 9506942

Disease

[IGKC_HUMAN] Defects in IGKC are the cause of immunoglobulin kappa light chain deficiency (IGKCD) [MIM:614102]. IGKCD is a disease characterized by the complete absence of immunoglobulin kappa chains.[1]

About this Structure

1a4j is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Romesberg FE, Spiller B, Schultz PG, Stevens RC. Immunological origins of binding and catalysis in a Diels-Alderase antibody. Science. 1998 Mar 20;279(5358):1929-33. PMID:9506942
  1. ↑ Stavnezer-Nordgren J, Kekish O, Zegers BJ. Molecular defects in a human immunoglobulin kappa chain deficiency. Science. 1985 Oct 25;230(4724):458-61. PMID:3931219

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