2kb4

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Template:STRUCTURE 2kb4

Contents

NMR structure of the unphosphorylated form of OdhI, OdhI.

Template:ABSTRACT PUBMED 19368890

Function

[ODHI_CORGL] An essential component of the PknG signaling pathway. When unphosphorylated, it inhibits the activity of 2-oxoglutarate dehydrogenase. When phosphorylated it does not inhibit 2-oxoglutarate dehydrogenase.

About this Structure

2kb4 is a 1 chain structure with sequence from Corynebacterium glutamicum. Full experimental information is available from OCA.

Reference

  • Barthe P, Roumestand C, Canova MJ, Kremer L, Hurard C, Molle V, Cohen-Gonsaud M. Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism. Structure. 2009 Apr 15;17(4):568-78. PMID:19368890 doi:10.1016/j.str.2009.02.012

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