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3iwu

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Template:STRUCTURE 3iwu

Contents

Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase

Template:ABSTRACT PUBMED 16952372

Function

[HIUH_DANRE] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

About this Structure

3iwu is a 8 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.

Reference

  • Zanotti G, Cendron L, Ramazzina I, Folli C, Percudani R, Berni R. Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter. J Mol Biol. 2006 Oct 13;363(1):1-9. Epub 2006 Aug 2. PMID:16952372 doi:10.1016/j.jmb.2006.07.079

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OCA

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