3it5

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Template:STRUCTURE 3it5

Contents

Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa

Template:ABSTRACT PUBMED 20026068

Function

[LASA_PSEAE] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.

About this Structure

3it5 is a 4 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Spencer J, Murphy LM, Conners R, Sessions RB, Gamblin SJ. Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J Mol Biol. 2010 Mar 5;396(4):908-23. Epub 2009 Dec 21. PMID:20026068 doi:10.1016/j.jmb.2009.12.021

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