3irc
From Proteopedia
Crystal structure analysis of dengue-1 envelope protein domain III
Function
[Q9J7C6_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
About this Structure
3irc is a 1 chain structure with sequence from Dengue virus 1. This structure supersedes the now removed PDB entry 3egp. Full crystallographic information is available from OCA.
Categories: Dengue virus 1 | CSGID, Center for Structural Genomics of Infectious Diseases. | Chruszcz, M. | Fremont, D H. | Kim, T. | Minor, W. | Nelson, C A. | Warren, J T. | Atp-binding | Center for structural genomics of infectious disease | Csgid | Envelope | Envelope protein | Helicase | Hydrolase | Membrane | Nucleotide-binding | Rna replication | Structural genomic | Transmembrane | Viral protein | Virion | Virus
