3owg

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Template:STRUCTURE 3owg

Contents 1 Crystal structure of vaccinia virus Polyadenylate polymerase(vp55) 2 Function 3 About this Structure 4 Reference

Crystal structure of vaccinia virus Polyadenylate polymerase(vp55)

Template:ABSTRACT PUBMED 23519670

Function

[PAP1_VACCW] Polymerase that creates the 3'-poly(A) tail of mRNA's.

About this Structure

3owg is a 2 chain structure with sequence from Vaccinia virus wr. Full crystallographic information is available from OCA.

Reference

• Moure CM, Bowman BR, Gershon PD, Quiocho FA. Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol Cell. 2006 May 5;22(3):339-49. PMID:16678106 doi:10.1016/j.molcel.2006.03.015
• Li C, Li H, Zhou S, Sun E, Yoshizawa J, Poulos TL, Gershon PD. Polymerase translocation with respect to single-stranded nucleic acid: looping or wrapping of primer around a poly(A) polymerase. Structure. 2009 May 13;17(5):680-9. PMID:19446524 doi:10.1016/j.str.2009.03.012