2yn0

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Template:STRUCTURE 2yn0

Contents 1 tau55 histidine phosphatase domain 2 Function 3 About this Structure 4 Reference

tau55 histidine phosphatase domain

Function

[TFC7_YEAST] TFIIIC mediates tRNA and 5S RNA gene activation by binding to intragenic promoter elements. Upstream of the transcription start site, TFIIIC assembles the initiation complex TFIIIB-TFIIIC-tDNA, which is sufficient for RNA polymerase III recruitment and function. Part of the tauA domain of TFIIIC that binds boxA DNA promoter sites of tRNA and similar genes.^[1]

About this Structure

2yn0 is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

1. ↑ Manaud N, Arrebola R, Buffin-Meyer B, Lefebvre O, Voss H, Riva M, Conesa C, Sentenac A. A chimeric subunit of yeast transcription factor IIIC forms a subcomplex with tau95. Mol Cell Biol. 1998 Jun;18(6):3191-200. PMID:9584160