3k7r

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Template:STRUCTURE 3k7r

Contents

Crystal structure of [TM][CuAtx1]3

Template:ABSTRACT PUBMED 19965379

Function

[ATX1_YEAST] Shuttles copper to the transport ATPase CCC2. Protects against oxygen toxicity.

About this Structure

3k7r is a 12 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Alvarez HM, Xue Y, Robinson CD, Canalizo-Hernandez MA, Marvin RG, Kelly RA, Mondragon A, Penner-Hahn JE, O'Halloran TV. Tetrathiomolybdate inhibits copper trafficking proteins through metal cluster formation. Science. 2010 Jan 15;327(5963):331-4. Epub 2009 Nov 26. PMID:19965379 doi:10.1126/science.1179907

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