3kn2
From Proteopedia
HCV NS3 Protease Domain with ketoamide inhibitor
Template:ABSTRACT PUBMED 20004570
About this Structure
3kn2 is a 4 chain structure with sequence from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.
Reference
- Nair LG, Sannigrahi M, Bogen S, Pinto P, Chen KX, Prongay A, Tong X, Cheng KC, Girijavallabhan V, George Njoroge F. P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile. Bioorg Med Chem Lett. 2010 Jan 15;20(2):567-70. Epub 2009 Nov 22. PMID:20004570 doi:10.1016/j.bmcl.2009.11.094
Categories: Hepatitis c virus subtype 1a | Bogen, S. | Chen, K X. | Nair, L G. | Njoroge, G. | Pinto, P. | Prongay, A. | Sannigrahi, M. | Atp-binding | Capsid protein | Envelope protein | Helicase | Hepatitis c virus | Host membrane | Hydrolase | Ketoamide inhibitor | Membrane | Ns3 protease domain | Nucleotide-binding | Rna replication | Serine protease | Transmembrane | Virion
