3lg5

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Template:STRUCTURE 3lg5

Contents

F198A Epi-isozizaene synthase: Complex with Mg, inorganic pyrophosphate and benzyl triethyl ammonium cation

Template:ABSTRACT PUBMED 20131801

Function

[CYC1_STRCO] Catalyzes the cyclization of farnesyl diphosphate (FPP) to the sesquiterpene epi-isozizaene.

About this Structure

3lg5 is a 1 chain structure with sequence from Streptomyces coelicolor. Full crystallographic information is available from OCA.

Reference

  • Aaron JA, Lin X, Cane DE, Christianson DW. Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates. Biochemistry. 2010 Mar 2;49(8):1787-97. PMID:20131801 doi:10.1021/bi902088z

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