3l9b
From Proteopedia
Crystal Structure of Rat Otoferlin C2A
Function
[OTOF_RAT] Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. Interacts in a calcium-dependent manner to the presynaptic SNARE proteins at ribbon synapses of cochlear inner hair cells (IHCs) to trigger exocytosis of neurotransmitter. Also essential to synaptic exocytosis in immature outer hair cells (OHCs). May also play a role within the recycling of endosomes (By similarity).
About this Structure
3l9b is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
