4hva

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Template:STRUCTURE 4hva

Mechanistic and Structural Understanding of Uncompetitive Inhibitors of Caspase-6

Template:ABSTRACT PUBMED 23227217

Function

[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.

About this Structure

4hva is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

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