4iar
From Proteopedia
Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)
Template:ABSTRACT PUBMED 23519210
Function
[5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
About this Structure
4iar is a 1 chain structure. Full crystallographic information is available from OCA.
Categories: Bai, F. | Cherezov, V. | GPCR, GPCR Network. | Gao, X. | Han, G W. | Huang, X. | Jiang, H. | Jiang, Y. | Katritch, V. | Liu, W. | Ma, J. | McCorvy, J D. | Melcher, K. | Roth, B L. | Stevens, R C. | Vardy, E. | Wacker, D. | Wang, C. | Wu, H. | Xu, H E. | Yang, H. | Yang, L. | Zhang, C. | Zhou, E X. | Electron transport | Ergotamine | Gpcr | Gpcr dock | Gpcr network | Membrane protein | Novel protein engineering | Psi-biology | Signaling protein | Structural genomic
