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4hno

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Revision as of 21:54, 10 April 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4hno

High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima

Template:ABSTRACT PUBMED 23355472

Function

[END4_THEMA] Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity).

About this Structure

4hno is a 1 chain structure with sequence from Thermotoga maritima msb8. Full crystallographic information is available from OCA.

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