3vdo
From Proteopedia
Structure of extra-cytoplasmic function(ECF) sigma factor SigK in complex with its negative regulator RskA from Mycobacterium tuberculosis
Function
[SIGK_MYCTU] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-K controls genes such as mpt70 and mpt83. [RSKA_MYCTU] Represses SigK, the extracytoplasmic function (ECF) sigma factor K, by binding to it and inhibiting its activity. This leads to a decreased expression of SigK-regulated genes, such as mpt70 and mpt83.
About this Structure
3vdo is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
