3mb5

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Template:STRUCTURE 3mb5

Contents 1 Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine 2 Function 3 About this Structure 4 Reference

Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine

Template:ABSTRACT PUBMED 20483913

Function

[Q9V1J7_PYRAB] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence.^{[1] [2]}

About this Structure

3mb5 is a 1 chain structure with sequence from Pyrococcus abyssi. Full crystallographic information is available from OCA.

Reference

• Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B. Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Nucleic Acids Res. 2010 May 18. PMID:20483913 doi:10.1093/nar/gkq381
• Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L. A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res. 2004 Jan 22;32(2):465-76. Print 2004. PMID:14739239 doi:10.1093/nar/gkh191

1. ↑ Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L. A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res. 2004 Jan 22;32(2):465-76. Print 2004. PMID:14739239 doi:10.1093/nar/gkh191
2. ↑ Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B. Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Nucleic Acids Res. 2010 May 18. PMID:20483913 doi:10.1093/nar/gkq381