3m4g

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Template:STRUCTURE 3m4g

Contents

H57A HFQ from Pseudomonas Aeruginosa

Template:ABSTRACT PUBMED 20606268

Function

[HFQ_PSEAE] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity).

About this Structure

3m4g is a 12 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Moskaleva O, Melnik B, Gabdulkhakov A, Garber M, Nikonov S, Stolboushkina E, Nikulin A. The structures of mutant forms of Hfq from Pseudomonas aeruginosa reveal the importance of the conserved His57 for the protein hexamer organization. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jul 1;66(Pt, 7):760-4. Epub 2010 Jun 23. PMID:20606268 doi:10.1107/S1744309110017331

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