4i77
From Proteopedia
Contents |
Lebrikizumab Fab bound to IL-13
Template:ABSTRACT PUBMED 23357170
Disease
[IL13_HUMAN] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
Function
[IL13_HUMAN] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
About this Structure
4i77 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
