4fgh

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Template:STRUCTURE 4fgh

S. aureus dihydrofolate reductase co-crystallized with ethyl-DAP isobutenyl-dihydrophthalazine inhibitor

Template:ABSTRACT PUBMED 22930550

Function

[DYR_STAAU] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4fgh is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA.

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