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4bhb
From Proteopedia
Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE
Template:ABSTRACT PUBMED 23564173
Function
[OGT_MYCTU] Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated (By similarity).
About this Structure
4bhb is a 1 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.
