3mzs

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Template:STRUCTURE 3mzs

Contents

Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol

Template:ABSTRACT PUBMED 21159775

Function

[CP11A_BOVIN] Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.

About this Structure

3mzs is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Mast N, Annalora AJ, Lodowski DT, Palczewski K, Stout CD, Pikuleva IA. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2010 Dec 15. PMID:21159775 doi:10.1074/jbc.M110.188433

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