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3n5a

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Revision as of 21:05, 17 April 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 3n5a

Contents

Synaptotagmin-7, C2B-domain, calcium bound

Template:ABSTRACT PUBMED 20824061

Function

[SYT7_MOUSE] May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (By similarity).

About this Structure

3n5a is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Xue M, Craig TK, Shin OH, Li L, Brautigam CA, Tomchick DR, Sudhof TC, Rosenmund C, Rizo J. Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. PLoS One. 2010 Sep 2;5(9). pii: e12544. PMID:20824061 doi:10.1371/journal.pone.0012544

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OCA

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