3mla

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Template:STRUCTURE 3mla

Contents 1 BaNadD in complex with inhibitor 1_02 2 Function 3 About this Structure 4 Reference

BaNadD in complex with inhibitor 1_02

Template:ABSTRACT PUBMED 020578699

Function

[NADD_BACAC] Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity).

About this Structure

3mla is a 2 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

• Huang N, Kolhatkar R, Eyobo Y, Sorci L, Rodionova I, Osterman AL, Mackerell AD, Zhang H. Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement. J Med Chem. 2010 Jul 22;53(14):5229-39. PMID:20578699 doi:10.1021/jm100377f