3my2

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Template:STRUCTURE 3my2

Contents

Crystal structure of LptC

Template:ABSTRACT PUBMED 20720015

Function

[LPTC_ECOLI] Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. It facilitates the transfer of LPS from the inner membrane to a periplasmic chaperone, LptA.[1] [2] [3]

About this Structure

3my2 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Tran AX, Dong C, Whitfield C. Structure and functional analysis of LptC, a conserved membrane protein involved in the lipopolysaccharide export pathway in Escherichia coll. J Biol Chem. 2010 Aug 18. PMID:20720015 doi:10.1074/jbc.M110.144709
  1. ↑ Sperandeo P, Pozzi C, Deho G, Polissi A. Non-essential KDO biosynthesis and new essential cell envelope biogenesis genes in the Escherichia coli yrbG-yhbG locus. Res Microbiol. 2006 Jul-Aug;157(6):547-58. Epub 2006 Feb 9. PMID:16765569 doi:10.1016/j.resmic.2005.11.014
  2. ↑ Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A. Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli. J Bacteriol. 2008 Jul;190(13):4460-9. Epub 2008 Apr 18. PMID:18424520 doi:JB.00270-08
  3. ↑ Tran AX, Dong C, Whitfield C. Structure and functional analysis of LptC, a conserved membrane protein involved in the lipopolysaccharide export pathway in Escherichia coll. J Biol Chem. 2010 Aug 18. PMID:20720015 doi:10.1074/jbc.M110.144709

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