2wlv

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Template:STRUCTURE 2wlv

Contents 1 Structure of the N-terminal capsid domain of HIV-2 2 Function 3 About this Structure 4 See Also 5 Reference

Structure of the N-terminal capsid domain of HIV-2

Template:ABSTRACT PUBMED 19767750

Function

[Q76929_9HIV2] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS012344_004_008806] Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).

About this Structure

2wlv is a 2 chain structure with sequence from Human immunodeficiency virus type 2 (isolate d194). Full crystallographic information is available from OCA.

See Also

• Gag polyprotein

Reference

• Price AJ, Marzetta F, Lammers M, Ylinen LM, Schaller T, Wilson SJ, Towers GJ, James LC. Active site remodeling switches HIV specificity of antiretroviral TRIMCyp. Nat Struct Mol Biol. 2009 Oct;16(10):1036-42. Epub 2009 Sep 20. PMID:19767750 doi:10.1038/nsmb.1667