4h49
From Proteopedia
Crystal structure of the catalytic domain of MMP-12 in complex with a twin inhibitor.
Template:ABSTRACT PUBMED 23567804
Function
[MMP12_HUMAN] May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
About this Structure
4h49 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
