3o7a

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Template:STRUCTURE 3o7a

Contents

Crystal structure of PHF13 in complex with H3K4me3

Function

[Q59FB6_HUMAN] Modulates chromatin structure. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis.[1]

About this Structure

3o7a is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Kinkley S, Staege H, Mohrmann G, Rohaly G, Schaub T, Kremmer E, Winterpacht A, Will H. SPOC1: a novel PHD-containing protein modulating chromatin structure and mitotic chromosome condensation. J Cell Sci. 2009 Aug 15;122(Pt 16):2946-56. doi: 10.1242/jcs.047365. Epub 2009, Jul 28. PMID:19638409 doi:10.1242/jcs.047365

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