3nkv

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3nkv

Contents 1 Crystal structure of Rab1b covalently modified with AMP at Y77 2 Function 3 About this Structure 4 Reference

Crystal structure of Rab1b covalently modified with AMP at Y77

Template:ABSTRACT PUBMED 20651120

Function

[RAB1B_HUMAN] Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.^[1]

About this Structure

3nkv is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Muller MP, Peters H, Blumer J, Blankenfeldt W, Goody RS, Itzen A. The Legionella effector protein DrrA AMPylates the membrane traffic regulator Rab1b. Science. 2010 Aug 20;329(5994):946-9. Epub 2010 Jul 22. PMID:20651120 doi:10.1126/science.1192276

1. ↑ Overmeyer JH, Wilson AL, Erdman RA, Maltese WA. The putative "switch 2" domain of the Ras-related GTPase, Rab1B, plays an essential role in the interaction with Rab escort protein. Mol Biol Cell. 1998 Jan;9(1):223-35. PMID:9437002