3o2d

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Template:STRUCTURE 3o2d

Contents

Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody

Template:ABSTRACT PUBMED 21134642

Function

[CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.

About this Structure

3o2d is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 8;18(12):1632-41. PMID:21134642 doi:10.1016/j.str.2010.09.017

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OCA

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