3nm4

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Template:STRUCTURE 3nm4

Contents 1 Helicobacter pylori MTAN 2 Function 3 About this Structure 4 Reference

Helicobacter pylori MTAN

Template:ABSTRACT PUBMED 20954236

Function

[MTNN_HELPJ] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).

About this Structure

3nm4 is a 2 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

Reference

• Ronning DR, Iacopelli NM, Mishra V. Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. Protein Sci. 2010 Oct 15. PMID:20954236 doi:10.1002/pro.524