3okc

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Template:STRUCTURE 3okc

Contents 1 Crystal structure of Corynebacterium glutamicum PimB' bound to GDP (orthorhombic crystal form) 2 Function 3 About this Structure 4 Reference

Crystal structure of Corynebacterium glutamicum PimB' bound to GDP (orthorhombic crystal form)

Template:ABSTRACT PUBMED 20843801

Function

[PIMB_CORGL] Catalyzes the addition of a mannose residue from GDP-D-mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose residues (PIM2). Can also add a mannose residue to the position 2 of a phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol mannoside (PIM1).

About this Structure

3okc is a 1 chain structure with sequence from Corynebacterium glutamicum. Full crystallographic information is available from OCA.

Reference

• Batt SM, Jabeen T, Mishra AK, Veerapen N, Krumbach K, Eggeling L, Besra GS, Futterer K. Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: Structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB' J Biol Chem. 2010 Sep 15. PMID:20843801 doi:10.1074/jbc.M110.165407