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3pa8

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Template:STRUCTURE 3pa8

Structure of the C. difficile TcdB cysteine protease domain in complex with a peptide inhibitor

Template:ABSTRACT PUBMED 21095570

About this Structure

3pa8 is a 2 chain structure with sequence from Clostridium difficile 630. Full crystallographic information is available from OCA.

Reference

  • Puri AW, Lupardus PJ, Deu E, Albrow VE, Garcia KC, Bogyo M, Shen A. Rational design of inhibitors and activity-based probes targeting Clostridium difficile virulence factor TcdB. Chem Biol. 2010 Nov 24;17(11):1201-11. PMID:21095570 doi:10.1016/j.chembiol.2010.09.011

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