3opg

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Template:STRUCTURE 3opg

Contents

Crystal structure of human Mitochondrial Transcription Termination Factor 3

Function

[MTER1_HUMAN] Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).[1]

About this Structure

3opg is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3my3. Full crystallographic information is available from OCA.

Reference

  1. ↑ Park CB, Asin-Cayuela J, Camara Y, Shi Y, Pellegrini M, Gaspari M, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Falkenberg M, Gustafsson CM, Larsson NG. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell. 2007 Jul 27;130(2):273-85. PMID:17662942 doi:10.1016/j.cell.2007.05.046

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