3q36

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Template:STRUCTURE 3q36

Contents

Crystal structure of the 4Fe-4S cluster domain of human DNA primase large subunit

Template:ABSTRACT PUBMED 21346410

Function

[PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

About this Structure

3q36 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Agarkar VB, Babayeva ND, Pavlov YI, Tahirov TH. Crystal structure of the C-terminal domain of human DNA primase large subunit: Implications for the mechanism of the primase - polymerase alpha switch. Cell Cycle. 2011 Mar 15;10(6). PMID:21346410

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