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3q0s
From Proteopedia
Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with erk2 NRE
Template:ABSTRACT PUBMED 021397187
Function
[PUM2_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
About this Structure
3q0s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
