This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3q0s
From Proteopedia
Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with erk2 NRE
Template:ABSTRACT PUBMED 021397187
Function
[PUM2_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
About this Structure
3q0s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
