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3ax2

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Template:STRUCTURE 3ax2

Contents

Crystal structure of rat TOM20-ALDH presequence complex: a disulfide-tethered complex with a non-optimized, long linker

Template:ABSTRACT PUBMED 21591667

Function

[TOM20_RAT] Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).

About this Structure

3ax2 is a 8 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Saitoh T, Igura M, Miyazaki Y, Ose T, Maita N, Kohda D. Crystallographic snapshots of tom20-mitochondrial presequence interactions with disulfide-stabilized peptides. Biochemistry. 2011 Jun 21;50(24):5487-96. Epub 2011 May 26. PMID:21591667 doi:10.1021/bi200470x

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OCA

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