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3pp2
From Proteopedia
Crystal structure of the pleckstrin homology domain of ArhGAP27
Function
[RHG27_HUMAN] Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).
About this Structure
3pp2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Arrowsmith, C H. | Bountra, C. | Edwards, A M. | Li, Y. | Nedyalkova, L. | Park, H. | SGC, Structural Genomics Consortium. | Shen, L. | Tempel, W. | Tong, Y. | Weigelt, J. | Wernimont, A K. | Gtpase activator | Hydrolase activator | Ph domain | Pleckstrin homology domain | Sgc | Structural genomics consortium
