3pyi

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Template:STRUCTURE 3pyi

Contents 1 Structure of the N-terminal domain of C. elegans SAS-6 2 Function 3 About this Structure 4 Reference

Structure of the N-terminal domain of C. elegans SAS-6

Template:ABSTRACT PUBMED 21277013

Function

[SAS6_CAEEL] Required for centrosome duplication. Participates in centriole assembly.^{[1] [2]}

About this Structure

3pyi is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

• Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, Bortfeld M, Erat MC, Fluckiger I, Gonczy P, Steinmetz MO. Structural basis of the 9-fold symmetry of centrioles. Cell. 2011 Feb 4;144(3):364-75. PMID:21277013 doi:10.1016/j.cell.2011.01.008

1. ↑ Dammermann A, Muller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec;7(6):815-29. PMID:15572125 doi:S1534580704003806
2. ↑ Leidel S, Delattre M, Cerutti L, Baumer K, Gonczy P. SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells. Nat Cell Biol. 2005 Feb;7(2):115-25. PMID:15665853 doi:ncb1220