3qik
From Proteopedia
Crystal structure of the first PDZ domain of PREX1
Function
[PREX1_HUMAN] Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
About this Structure
3qik is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
