4fw2

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Template:STRUCTURE 4fw2

Crystal structure of RSV three-domain integrase with disordered N-terminal domain

Template:ABSTRACT PUBMED 23451105

Function

[POL_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).

About this Structure

4fw2 is a 2 chain structure with sequence from Rous sarcoma virus - prague c. Full crystallographic information is available from OCA.

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