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4gzd

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Revision as of 07:22, 16 May 2013 by OCA (Talk | contribs)
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Template:STRUCTURE 4gzd

Contents

Crystal structure of yeast Ent2 ENTH domain triple mutant N112D,S114E, E118Q

Template:ABSTRACT PUBMED 23553749

Function

[ENT2_YEAST] Binds to membranes enriched in phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) and phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Required for endocytosis and localization of actin.[1]

About this Structure

4gzd is a 1 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  1. ↑ Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. EMBO J. 1999 Aug 16;18(16):4383-93. PMID:10449404 doi:10.1093/emboj/18.16.4383

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