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2kzh
From Proteopedia
Contents |
Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli
Template:ABSTRACT PUBMED 21354426
Function
[TRPC_ECOLI] Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
About this Structure
2kzh is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.
Reference
- Setiyaputra S, Mackay JP, Patrick WM. The structure of a truncated phosphoribosylanthranilate isomerase suggests a unified model for evolution of the (betaalpha)8 barrel fold. J Mol Biol. 2011 Apr 29;408(2):291-303. Epub 2011 Feb 25. PMID:21354426 doi:10.1016/j.jmb.2011.02.048
- Patrick WM, Blackburn JM. In vitro selection and characterization of a stable subdomain of phosphoribosylanthranilate isomerase. FEBS J. 2005 Jul;272(14):3684-97. PMID:16008567 doi:10.1111/j.1742-4658.2005.04794.x
